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Article: Context-Dependent Modulation of GABAAR-Mediated Tonic Currents.

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Patel B; Bright DP; Mortensen M; Frølund B; Smart TG
J. Neurosci., 2016


Table 3.

sIPSC parameters for cerebellar granule, CA1 hippocampal, and dLGN relay neurons in acute slices

CGCs CA1 pyramidal neurons dLGN relay neurons
Inward 4-PIOL Outward 4-PIOL
Control +4-PIOL Control +4-PIOL Control +4-PIOL Control +4-PIOL
Frequency, Hz 1.5 ± 0.3 1.1 ± 0.2* 2.0 ± 0.5 1.1 ± 0.3* 0.6 ± 0.1 0.6 ± 0.1 11.5 ± 1.6 1.5 ± 0.3**
Amplitude, pA 185 ± 36 120 ± 14* 49 ± 13 31 ± 4 20 ± 2 17 ± 2* 56.4 ± 4.3 40.2 ± 2.7*
10-90% rise time, ms 0.9 ± 0.1 0.9 ± 0.1 1.2 ± 0.2 1.0 ± 0.1 1.2 ± 0.2 1.0 ± 0.2
Decay tau, ms 18.4 ± 3.1 18.7 ± 2.5 23.9 ± 2.2 22.7 ± 3.0 21.5 ± 1.6 19.7 ± 2.1

  • All data are presented as mean ± SEM (n = 4-8). Values for CA1 pyramidal neurons are divided according to direction of 4-PIOL response. Control and 4-PIOL data were compared using a paired t test.

  • ↵* p < 0.05,

  • ↵** p < 0.01.


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Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source